Based on the latest Bureau of Labor Statistics OEWS data — updated August 12, 2026.
| South Carolina | National | Difference | |
|---|---|---|---|
| Median annual salary | $82,360 | $98,331 | -16% |
| Median hourly wage | $39.60 | $47.27 | -16% |
Adjusted for local price levels (100 = national average), the cost-adjusted median is $87,898.
| City | Median | Entry Level | Experienced | Cost of Living |
|---|---|---|---|---|
| City-level data coming soon. | ||||
The median annual salary for a Registered Nurse in South Carolina is $82,360, or about $39.60 per hour, according to BLS OEWS data.
The national median for Registered Nurses is $98,331. South Carolina is -16% below the national median.
Entry-level registered nurses in South Carolina typically earn from varies by experience depending on the city and employer.
With 49,750 registered nurse jobs on record and a median salary of $82,360, South Carolina offers competitive pay compared to the rest of the country.