Nurse Practitioner Salary in South Carolina (2026)

Based on the latest Bureau of Labor Statistics OEWS data — updated September 10, 2026.

Median Annual Salary$123,290
Median Hourly Wage$59.27
National Median$135,791
Jobs in South Carolina5,670

Nurse Practitioner Salary in South Carolina vs. National Average

South CarolinaNationalDifference
Median annual salary$123,290$135,791-9%
Median hourly wage$59.27$65.28-9%

Adjusted for local price levels (100 = national average), the cost-adjusted median is $131,580.

Nurse Practitioner Salary in Top South Carolina Cities

CityMedianEntry LevelExperiencedCost of Living
City-level data coming soon.

FAQ

How much does a Nurse Practitioner make in South Carolina?

The median annual salary for a Nurse Practitioner in South Carolina is $123,290, or about $59.27 per hour, according to BLS OEWS data.

How does this compare to the national average?

The national median for Nurse Practitioners is $135,791. South Carolina is -9% below the national median.

What is the entry-level salary for a Nurse Practitioner in South Carolina?

Entry-level nurse practitioners in South Carolina typically earn from varies by experience depending on the city and employer.

Is South Carolina a good state for nurse practitioners?

With 5,670 nurse practitioner jobs on record and a median salary of $123,290, South Carolina offers competitive pay compared to the rest of the country.

Where does Nurse Practitioner pay rank in South Carolina?

By median annual wage, nurse practitioners rank 53 of the 713 occupations reported in South Carolina — higher than 93% of them.

What do similar occupations pay in South Carolina?

Among occupations in the same job family, General Internal Medicine Physicians at $359,500, Neurologists at $352,680, Emergency Medicine Physicians at $341,960 — all figures are median annual wages for South Carolina.

Do these figures include taxes?

No. Every figure on this page is a gross (pre-tax) wage. South Carolina levies a state income tax, so take-home pay is lower than the gross figures shown here. The state's cost of living index is 95.0 (100 = national average).

Nurse Practitioner in South Carolina: where it sits among all occupations

By median annual wage, nurse practitioners rank 53 of the 713 occupations reported in South Carolina — higher than 93% of them.

Occupation in the same job familyMedian in South CarolinaJobs
General Internal Medicine Physicians$359,500$1,260
Neurologists$352,680$40
Emergency Medicine Physicians$341,960$80
Orthodontists$311,450—
Obstetricians and Gynecologists$302,340$350
Physicians, All Other$274,480$4,510

South Carolina levies a state income tax, so take-home pay is lower than the gross figures shown here. The state's cost of living index is 95.0 (100 = national average).

Ranking and comparison figures come from the same BLS OEWS release as the rest of this page, which covers 713 occupations in South Carolina.