Based on the latest Bureau of Labor Statistics OEWS data — updated August 12, 2026.
| Missouri | National | Difference | |
|---|---|---|---|
| Median annual salary | $81,780 | $98,331 | -17% |
| Median hourly wage | $39.32 | $47.27 | -17% |
Adjusted for local price levels (100 = national average), the cost-adjusted median is $90,066.
| City | Median | Entry Level | Experienced | Cost of Living |
|---|---|---|---|---|
| Kansas City | $81,767 | $61,750 | $99,750 | 91 |
The median annual salary for a Registered Nurse in Missouri is $81,780, or about $39.32 per hour, according to BLS OEWS data.
The national median for Registered Nurses is $98,331. Missouri is -17% below the national median.
Entry-level registered nurses in Missouri typically earn from $61,750 depending on the city and employer.
With 76,310 registered nurse jobs on record and a median salary of $81,780, Missouri offers competitive pay compared to the rest of the country.